PhD Studentship: Correlative Imaging for Fracture Prediction in the Military

1 month ago


Southampton, United Kingdom University of Southampton Full time

Supervisory Team: Claire Clarkin, Nicholas Fuggle, Jemma Kerns (University of Lancaster),

Project description:

Funding for this project is offered by the Centre for Doctoral Training in Complex Integrated Systems for Defence & Security (CISDnS), which will recruit motivated and inquisitive candidates across the themes of Digital, Physical and Biological systems to provide a diverse and interconnected cohort training environment. As well as carrying out research training in a world-leading research group, membership of CISDnS will provide the opportunity for you to be exposed and trained to handle the interdisciplinary challenges faced in the real-world via a Systems Thinking approach. You will learn about the wider challenges of research and innovation within the Defence & Security sector from both your peers and industry partners.

Research project: Hormonal contraceptive use is common in the military and low endogenous oestradiol caused by hormonal contraceptives in  women  could negatively impact bone structure, adaptation to exercise, and stress fracture risk. The effect of these contraceptives not only on the skeletal composition but also on the cellular function are poorly characterised. With the increasing prevalence of predictive modelling, there is an opportunity to develop comprehensive models that can integrate hormonal profiles, physical training regimens, and skeletal health data to better understand and predict the impact of hormonal contraceptive use on bone physiology and stress fracture risk in female soldiers.

This PhD studentship offers an exciting opportunity to investigate the impact of arduous exercise and contraceptive use on bone health. The gathered data will be used to develop predictive models of fracture risk for both men and women undergoing military training. Additionally, these proof-of-concept models hold potential for broader application, aiding in the assessment of fracture risk across various non-military populations.

This project offers a unique interdisciplinary programme at the life science, biomedical science, and computer science interface based the Faculty of the Environment and Life Sciences at the University of Southampton. The ideal candidate will have biomedical (imaging) experience, experience with tissue culture techniques, intermediate programming ability and some knowledge of the applications of machine learning models.

Entry Requirements

A very good undergraduate degree (at least a UK 2:1 honours degree, or its international equivalent).

Closing date: 31st August 2024. Applications will be considered in the order that they are received, the position will be considered filled when a suitable candidate has been identified.

Funding: Full-time studentships will cover UK course fees and an enhanced tax-free stipend of approx. £23,500 per year for 4 years along with a substantial budget for research, travel, and centre activities. A number of studentships are available and will be awarded on a rolling basis, so you are encouraged to apply early for the best opportunity to be considered.

How to apply

Apply online: Search for a Postgraduate Programme of Study (soton.ac.uk).

Select programme type (Research), 2024/25, Faculty of Physical Sciences and Engineering, next page select “Integrated PhD in Complex Integrated Systems for Defence and Security (2024-25)”, In Section 2 of the application form you should insert the name of the supervisor Claire Clarkin

Applications should include:

  • Curriculum Vitae
  • Two reference letters
  • Degree Transcripts/Certificates to date

For further information please contact: feps-pgr-apply@soton.ac.uk

Full-time studentships will cover UK course fees and an enhanced tax-free stipend of approx. £23,500 per year for 4 years along with a substantial budget for research, travel, and centre activities



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