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Biomarker Scientist

4 months ago


Slough Berkshire, United Kingdom CK Group- Science, Clinical and Technical Full time

CK Group are recruiting for a Biomarker Scientist to join a global pharmaceutical company, based in Slough on a contract basis initially for 12 months. Salary: Hourly: From £20.03 PAYE or £27.27 Umbrella Biomarker Scientist Role: Our client is recruiting for a high caliber scientist to join the team to support clinical transcriptomics as a Subject Matter Expert. The successful applicant will be responsible for planning and technical oversight of Biomarker Transcriptomics activities outsourced to CROs. Your Background: Candidates should have a BSc or higher academic qualification in a biological discipline with good theoretical understanding of the principals of molecular biology and transcriptomics (in particular RNA sequencing and RT-qPCR), and the application to biomarker analysis in clinical studies. Practical experience of the complete workflow for RNA sequencing experiments, from sample extraction, library preparation and quality control, sequencing runs, including troubleshooting. Practical experience in Molecular Biology methods, including RNA extraction from a variety of biofluids and tissue matrices, primer and probe design, quantitative PCR (real-time and/or ddPCR) and data analysis. Excellent organisation skills and attention to detail essential, alongside enthusiasm to strengthen existing workflows and reporting. Clear grasp of context of use (linking biomarker assay requirements to the usage of the data generated). Demonstrated ability to work flexibly in a dynamic environment to meet project needs and timelines with minimal supervision. Ability to work in a matrix team and communicate in a clear and timely manner with a wide range of internal and external stakeholders. Adaptable to changing project and organizational priorities, aligned with departmental needs. Preferred Experience of working in a pharmaceutical drug discovery and development environment. Experience of Protein analysis using O-LINK Experience working with Contract Research Organisations (CROs) to oversee method development, validation and/or sample analysis to agreed deadlines. Experience in tissue and biofluid collection, handling and storage in clinical settings. Experience of working with human tissue under the directives of the Human Tissue Act (HTA), and experience of working with samples and studies under GCP compliance. Practical experience in any of the following techniques would be an advantage: histology and immunohistochemistry, Immunoassay and ligand binding assays, Flow cytometry assays, LC-MS. Company: Our client is a is a global biopharmaceutical company focused on creating value for people living with severe diseases in immunology and neurology now and into the future. Location: This role is based at our clients site in Slough. Apply: It is essential that applicants hold entitlement to work in the UK. Please quote job reference (phone number removed) in all correspondence. Please note: This role may be subject to a satisfactory basic Disclosure and Barring Service (DBS) check