Senior QC Scientist

Job Title: Senior Scientist – Diagnostic Deployment
Cambridge Biomedical Campus, UK
Join a dedicated Oncology community that’s growing fast and building a strong track record of success. We are looking for a Senior Scientist to support diagnostic assay optimisation, deployment, analytical validation, and high-quality laboratory delivery within our accredited diagnostic laboratory at the Cambridge Biomedical Campus. The role centres on immunohistochemistry (IHC) and digital/computational pathology and includes building innovative diagnostic deployment strategies for prospective clinical testing.
You will develop, optimise, validate, and operationalise cutting-edge diagnostics including IHC, digital/computational pathology and molecular assays. You will ensure regulatory-compliant workflows (e.g., Working in matrix teams across AstraZeneca and with external laboratories and partners, you will ensure assay performance, timely reporting, and continuous improvement of processes and technologies.
Lead deployment and analytical validation of tissue and molecular diagnostics, with a focus on IHC and digital pathology.
Oversee prospective clinical testing end to end: maintain sample integrity, meet turnaround targets, ensure protocol compliance, and produce clear data and reports.
Keep operations audit‑ready: write and follow SOPs, qualify and maintain equipment, run reagent QC, manage inventory, and resolve deviations/CAPA.
Translate clinical and regulatory needs into validation plans; communicate decisions, risks, and mitigations.
Assess new technologies and plan deployment: evaluate feasibility, define validation strategies, integrate into workflows, set training, and deliver to agreed timelines.
Degree in Biomedical Science, Pathology, Molecular Biology or related field (MSc or equivalent experience).
Deep expertise in IHC assay development, optimisation, and validation within a regulated laboratory environment.
Experience with digital pathology (slide scanning, image QC) and an interest in deploying cutting-edge computational pathology solutions.
Hands-on experience performing diagnostic testing, including prospective clinical trial workflows and sample handling.
Knowledge of quality systems and accreditation standards (e.g., Strong data integrity and documentation skills, with proficiency in writing validation protocols/reports and SOPs.
Experience with algorithm evaluation/validation for image analysis and quantitative IHC scoring.
Experience with assay tech transfer to external labs and interaction with IVD regulatory authorities or auditors.
Prior work in CAP/CLIA or NHS diagnostic laboratories; At AstraZeneca each and every one of us is bold in the belief that science should be at the centre of everything we do. Science can change the way we see the world and how we can impact the diseases that impact us. Science compels us to bush the boundaries of what is possible. AstraZeneca is a place where free thinking and creativity fuel our determination to make a difference to people's lives through science. With us, you will not only impact the future of medicine but also enjoy competitive compensation, benefits, and robust career development opportunities. Are you ready to help eliminate cancer as a cause of death? Apply online before December 03 . Search “AstraZeneca Careers” on LinkedIn, Facebook, and Instagram to learn more about our culture and opportunities.
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We want people to feel they belong at AstraZeneca and Alexion, starting with our recruitment process. We offer reasonable adjustments/accommodations to help all candidates to perform at their best. If you have a need for any adjustments/accommodations, please complete the section in the application form.