Senior Biologist

Your work will change lives. As a key member of Recursion's partnership-facing data science team, you will be at the forefront of reimagining drug discovery from first principles using Recursion’s massive data and compute capabilities. As senior computational biologist, you will be supporting partnership portfolio of preclinical drug programs and be responsible for designing and executing analyses to support target nomination, validation, and early programs in immunology and inflammation (I&I) diseases, translationally validates disease contexts in hit-to-lead, and accelerates in vivo work in lead optimization.
You will integrate layers of Recursion platform data (phenomics, transcriptomics, proteomics, etc) to validate the link between target and disease biology and to propose targets and early programs in novel areas of immunology and inflammation. You will partner with biologists and medicinal chemists to build supporting data packets for targets from our phenomic maps, target screens, and partnered patient data sets. You will also collaborate with computational scientists from across the organization to develop, deploy, and scale novel approaches to: 1) translational validation in hit to lead, 2) mechanism-of-action identification/de-risking , and 3) build evidence for patient connectivity to match the medicines we are creating to the patients who need them.
Deliver biological insights on therapeutic candidates and disease biology from the analysis of high-dimensional (phenomics, transcriptomics, proteomics, patient-derived) datasets that support clinical development planning
Present data analysis to decision makers and stakeholders in a clear and compelling way that drives toward getting medicines to patients
Assess new data sources, develop and scale new analysis methods, and support key program decisions with the ultimate goal of bringing life-changing therapies to patients at unprecedented speed
Industrialize analysis approaches to not only solve for the current project, but also to accelerate future projects and scale the impact that we can have
Collaborate cross-functionally with Recursion’s data science, biology, medicinal chemistry, and platform, teams to further advance Recursion’s ability to interpret and translate large-scale data assets into therapeutic programs
Our group is a bold, agile, diverse collective of computational drug discovery scientists deeply focused on the singular goal of bringing new therapeutics into the clinic at an accelerated pace. We are a computational group that spans precision oncology, I&I (immunology and inflammation), and neuroscience and focuses on advancing novel, targeted therapies for these disease areas. We partner closely with our biologists and medicinal chemists to design and execute impactful and decisional data analysis for multiple programs. We are responsible for data strategy across the portfolio and supported by computational leadership in designing scalable and reproducible experiments that serve to advance multiple programs within the portfolio.
Our team collaborates extensively with computational biologists in other therapeutic areas (neurobiology, oncology, etc.) as well as data scientists and engineers from our core platform teams to provide a strong network of feedback and support.
PhD in a relevant field (computational biology, systems biology, bioinformatics, immunology/inflammation biology, immuno-oncology, etc.) with a very strong computational focus and 3+ years of experience in biotech or pharma industry OR MS in a relevant field and 5+ years of experience in biotech or pharma industry solving fundamental problems in immunology or drug discovery
Experience applying computational methods (including probabilistic, statistical, and/or machine learning techniques) to analyze and integrate matched human clinical and molecular data in a high-level programming language such as Python or R
Deep expertise in the analysis and data integration of one or more ‘omics data modalities (phenomics, transcriptomics, proteomics, genomics),Exceptional data visualization skills
Excellent cross-functional communication skills, including an ability to explain complex scientific concepts to a variety of audiences using a combination of plots, documents, and presentations
Strong understanding of patient genetics and historical druggability of disease-relevant pathways, including experience working with patient data
Experience with immunology and inflammation clinical trial biomarker analysis
Working Location & Compensation:
This is an office-based, hybrid position at our UK headquarters located in London, England . Employees are expected to work in the office at least 50% of the time.
You will also be eligible for an annual bonus and equity compensation, as well as a comprehensive benefits package.
We are unconstrained in our thinking, take calculated risks, and push boundaries, but never at the expense of ethics, science, or trust.
RXRX) is a clinical stage TechBio company leading the space by decoding biology to radically improve lives. Enabling its mission is the Recursion OS, a platform built across diverse technologies that continuously generate one of the world’s largest proprietary biological and chemical datasets. Recursion leverages sophisticated machine-learning algorithms to distill from its dataset a collection of trillions of searchable relationships across biology and chemistry unconstrained by human bias. By commanding massive experimental scale — up to millions of wet lab experiments weekly — and massive computational scale — owning and operating one of the most powerful supercomputers in the world, Recursion is uniting technology, biology and chemistry to advance the future of medicine.
Recursion is headquartered in Salt Lake City, where it is a founding member of BioHive, the Utah life sciences industry collective. Learn more at , or connect on X (formerly Twitter) and LinkedIn .
All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, age, disability, veteran status, or any other characteristic protected under applicable federal, state, local, or provincial human rights legislation.
Accommodations are available on request for candidates taking part in all aspects of the selection process.
Recursion Pharmaceuticals and its affiliate companies do not accept resumes from any source other than candidates. The submission of resumes by recruitment or staffing agencies to Recursion or its employees is strictly prohibited unless contacted directly by Recursion’s internal Talent Acquisition team.