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Associate Research Fellow

1 month ago


United Kingdom Imperial College London Full time

Research Associate
Job Type: Full-Time.
We are looking for a Postdoctoral Research Associate to join our group to work on projects related to the study of the subcellular signal organisation of the glucagon receptor family (GLP-1R, GCGR, GIPR), using state-of-the-art high-throughput screening techniques, high-resolution microscopy, and targeted biosensor approaches, as well as in vivo transgenic mouse models.
You will join a vibrant research group where you will help elucidate the molecular mechanisms governing the subcellular organisation of signalling of the glucagon receptor family of class B1 GPCRs in pancreatic islets and other metabolically relevant cell types (hepatocytes, adipocytes, etc).
Ongoing projects in our lab include:
You will employ molecular cell biology techniques such as CRISPR/Cas9 gene editing, high-resolution/super-resolution fluorescence and electron microscopy, multi-omic and high-throughput screening approaches, pharmacology methods, and cell type-specific/subcellular biosensor-based assays to characterise receptor signalling outputs from cell lines and primary cells/islets, as well as in vivo analysis of glucose handling in transgenic mice and/or mouse models of diet-induced diabetes.
Please visit the following link for further information about our lab:


PhD in molecular cell biology, or a related subject
Previous experience in high-resolution microscopy, molecular pharmacology and/or in vivo mouse modelling
Previous experience in pancreatic beta cell and islet biology

Full time, fixed term contract (24 months)
Possible hybrid working (min 60% on site)
The opportunity to continue your career at a world-leading institution and be part of our mission to continue science for humanity
Benefit from sector-leading salary and remuneration package (including 39 days off a year and generous pension schemes)
Get access to a range of workplace benefits including a flexible working policy from day 1, generous family leave packages, on-site leisure facilities and a cycle-to-work scheme
Interest-free season ticket loan schemes for travel
Be part of a diverse, inclusive, and collaborative work culture with various staff networks and resources designed to support your personal and professional wellbeing .
This is a full time role, based at our Hammersmith Campus.